HotSpot Therapeutics, Inc. is a biotechnology company pioneering the discovery and development of small molecule allosteric therapies targeting regulatory sites on proteins referred to as “natural hotspots visit website
T-knife is a biopharmaceutical company dedicated to developing novel therapeutics to fight cancer, initially focused on T cell receptor (TCR) engineered T cell therapies (TCR-Ts). visit website
Re-Inventing treatment of herpes infections.
Eyedrops for presbyopia visit website
Micro-organoid technology for precision cancer therapy and improved drug discovery visit website
Evommune is developing and discovering unique therapies that help patients with chronic inflammatory diseases
.
visit website
Egle Therapeutics is developing a game changer in the field of immunomodulating T-regulatory cells (Tregs) through the unique concept of Treg starving. visit website
Transformative therapeutics to preserve brain function and enhance resilience to neurodegenerative diseases. visit website
AviadoBio is developing and delivering transformative gene therapies for diseases including frontotemporal dementia (FTD) and amyotrophic lateral sclerosis (ALS). visit website
Perfuze is an Irish medical device company developing and commercializing new products for the treatment of ischemic stroke. visit website
Nobi is commercializing a silver tech platform enabling elderly people to live healthier at home, whereever that might be. visit website
New Amsterdam Pharma is developing lipid-lowering therapies for diseases with large unmet need. visit website
Neurent Medical is dedicated to developing highly innovative non-surgical interventions that treat chronic inflammatory Sino-Nasal diseases. visit website
OneProjects are developing VERAFEYE, a connected platform technology to revolutionise the treatment of AFib and cardiac arrhythmias. visit website
Dutch biotech company developing an innovative reversal agent for the treatment and prevention of severe bleeding in patients on oral anticoagulants. visit website
Dutch clinical stage biopharmaceutical company developing a treatment for acute kidney injury. visit website
FoRx Therapeutics focuses on drugging key molecular targets involved in the DNA Replication Stress as a new approach in the developments. visit website
Bringing knowledge, experience and science together to discover, develop and deliver therapies for CNS disorders. visit website
Belgian medical technology company focused on the development of novel ophthalmic implants for glaucoma visit website
US biotech company developing engineered natural killer (NK) cell therapies visit website
Amolyt Pharma is a company specialized in developing therapeutic peptides for rare endocrine and metabolic diseases
visit website
Imcyse develops active specific immunotherapies for the treatment and prevention of severe chronic diseases visit website
Young Paris based company pioneering enzymatic DNA synthesis visit website
Danish biotech startup using CRISPR-Cas to selectively eliminate specific bacterial strains visit website
Dutch biotech company commercializing an epilepsy drug with unprecedented efficacy for refractory patients with partial onset seizures.
visit website
Irish medical technology company commercializing garment-based pelvic floor muscle strengthening devices treating the cause of bladder leaks visit website
Digital health care company, leading in care pathway management visit website
US biopharmaceutical company focused on the development of novel gene therapy for unmet needs in advanced coronary artery disease visit website
Patient management platform for early detection of worsening heart failure visit website
Next generation DNA Damage Response (DDR) target pipeline with the potential to transform cancer therapy visit website
Novel therapeutic modality to induce functional knockdown of a target protein visit website
Medical device company focused on spine products visit website
Bioabsorbable vessel closure devices to enable minimally invasive heart procedures visit website
Next generation immuno-modulators acting on adaptive and innate immunity visit website
Therapies for heart failure and related Cardiovascular Diseases visit website
Developing treatments for patients with hyperoxaluria visit website
Developing Protein Therapeutics for High Unmet Medical needs visit website
Next-generation neo-epitope vaccines and oncolytic viruses visit website
Reversed Merger 2019
Therapies for autoimmune and immunology related diseases
visit website
Development of drugs for orphan diseases visit website
IPO 2019
Treatment of improper fluid balances in the body
visit website
Reversed Merger 2017
Developing Therapeutics to treat genetic diseases
visit website
IPO 2017
Therapies for lysosomal storage - and protein misfolding diseases
visit website
Acquired by Codman Neuro 2017
Innovative devices for minimally invasive stroke therapy
Acquired by Smith & Nephew 2017
First treatment healing rotator cuff disease
visit website
User-friendly, appealing and highly accurate insulin patch pump therapy for diabetes patients. visit website
mRNA immunotherapies for oncology and infectious diseases visit website
ONWARD is creating technologies to improve the movement, independence, and health of people with spinal cord injury. visit website
Spontaneous growth of natural heart valves and vessels visit website
Ultra-rapid diagnosis of infections visit website
IPO 2017
Innovative immunology treatments to improve the lives of people suffering from severe autoimmune diseases and cancer.
Acquired by Bruker 2017
Light sheet microscopy
visit website
IPO 2016
Innovative full-length bispecific and trispecific antibody therapeutics for oncology.
visit website
IPO 2016
Ultra-rapid diagnosis of infections
IPO 2016
Orthobiological products for tissue and fracture repair
visit website
Minimally invasive treatment of bone fractures visit website
Minimally invasive reshaping of heart valve visit website
Prevention of drug misadministration at the bedside visit website
Treatment of severe hospitalized Influenza visit website
Next-generation glucose measuring devices visit website
Acquired by BioMarin 2015
Development of drugs for Duchenne Muscular Dystrophy
Acquired by Agilent Technologies 2015
Commercialization of medical instruments and laboratory products
visit website
Acquired by Intrexon (now Precigen) 2015
Oral delivery of complex biological medicines
visit website
IPO 2015
Novell cell therapies
visit website
Acquired by Medtronic 2014
Medical device for treatment of Parkinson's disease
Acquired by Vectura 2014
Novel medical solutions for lung disease
visit website
IPO 2014
Development of drugs for Alzheimer's disease
IPO 2014
Innovative treatments for heart disease
IPO 2014
Innovative cancer treatments
Acquired by Agenus 2014
Innovative cancer treatments
Acquired by GSK 2013
Breakthrough vaccines for infectious diseases
Acquired by Salix 2013
Novel treatments for specialist care
Acquired by Ipsen 2013
Novel treatment options for pain and inflammation
Acquired by Dr Reddy 2013
Preparation and development of injectable drugs
Acquired by Syngenta 2013
Next-generation crop protection
Acquired by Post foods 2013
Commercialization of probiotic foodbars
Acquired by LDC
Novel drugs for psychiatric disorders
visit website
Acquired by Syngenta 2012
Advanced crop protection technologies
Acquired by Tigenix 2011
Innovative treatments for bowel disorders and other diseases
Acquired by Edwards 2010
Commercialization of cardiovascular monitoring devices
Acquired by C.R. Bard 2010
State-of-the-art medical devices for heart disease
Acquired by Shire 2010
Innovative treatments for bowel disease
IPO 2010
Novel treatment options for diabetes and other diseases
visit website
IPO 2010
Development of drugs for rare and serious diseases
Acquired by Cosmo 2009
Novel drugs for bladder disorders and inflammatory diseases
Acquired by Daiichi Sankyo 2008
Innovative cancer treatments
IPO 2007
Advanced platform technologies to enable the development of drugs
visit website
Acquired by Shire 2006
Development of drug for rare and fatal disease
Acquired by Pharming 2006
Products for medical problems associated with aging
Acquired by Astra Zeneca 2006
Innovative cancer treatments
IPO 2000
Development of vaccines
IPO 1999
Commercialization of vaccines for infectious disease
IPO 2000
Precise identification of diseases and disorders in humans
IPO 1996
Diagnostics and laboratory testing equipment
Acquired by Leica
Labeling and detection of biological molecules
visit website
Merged with U-Bisys into Crucell
Development of vaccines
Acquired by Bioness
Innovative rehabilitation products
IPO
Drug formulation
Acquired by Straumann
Commercialization of products used by dentists and oral surgeons
Merged with Introgene into Crucell
Innovative drug development platform
HotSpot Therapeutics, Inc. is a biotechnology company pioneering the discovery and development of small molecule allosteric therapies targeting regulatory sites on proteins referred to as “natural hotspots visit website
T-knife is a biopharmaceutical company dedicated to developing novel therapeutics to fight cancer, initially focused on T cell receptor (TCR) engineered T cell therapies (TCR-Ts). visit website
Re-Inventing treatment of herpes infections.
Eyedrops for presbyopia visit website
Micro-organoid technology for precision cancer therapy and improved drug discovery visit website
Evommune is developing and discovering unique therapies that help patients with chronic inflammatory diseases
.
visit website
Egle Therapeutics is developing a game changer in the field of immunomodulating T-regulatory cells (Tregs) through the unique concept of Treg starving. visit website
Transformative therapeutics to preserve brain function and enhance resilience to neurodegenerative diseases. visit website
AviadoBio is developing and delivering transformative gene therapies for diseases including frontotemporal dementia (FTD) and amyotrophic lateral sclerosis (ALS). visit website
Perfuze is an Irish medical device company developing and commercializing new products for the treatment of ischemic stroke. visit website
Nobi is commercializing a silver tech platform enabling elderly people to live healthier at home, whereever that might be. visit website
New Amsterdam Pharma is developing lipid-lowering therapies for diseases with large unmet need. visit website
Neurent Medical is dedicated to developing highly innovative non-surgical interventions that treat chronic inflammatory Sino-Nasal diseases. visit website
OneProjects are developing VERAFEYE, a connected platform technology to revolutionise the treatment of AFib and cardiac arrhythmias. visit website
Dutch biotech company developing an innovative reversal agent for the treatment and prevention of severe bleeding in patients on oral anticoagulants. visit website
Dutch clinical stage biopharmaceutical company developing a treatment for acute kidney injury. visit website
FoRx Therapeutics focuses on drugging key molecular targets involved in the DNA Replication Stress as a new approach in the developments. visit website
Bringing knowledge, experience and science together to discover, develop and deliver therapies for CNS disorders. visit website
Belgian medical technology company focused on the development of novel ophthalmic implants for glaucoma visit website
US biotech company developing engineered natural killer (NK) cell therapies visit website
Amolyt Pharma is a company specialized in developing therapeutic peptides for rare endocrine and metabolic diseases
visit website
Imcyse develops active specific immunotherapies for the treatment and prevention of severe chronic diseases visit website
Young Paris based company pioneering enzymatic DNA synthesis visit website
Danish biotech startup using CRISPR-Cas to selectively eliminate specific bacterial strains visit website
Dutch biotech company commercializing an epilepsy drug with unprecedented efficacy for refractory patients with partial onset seizures.
visit website
Irish medical technology company commercializing garment-based pelvic floor muscle strengthening devices treating the cause of bladder leaks visit website
Digital health care company, leading in care pathway management visit website
US biopharmaceutical company focused on the development of novel gene therapy for unmet needs in advanced coronary artery disease visit website
Patient management platform for early detection of worsening heart failure visit website
Next generation DNA Damage Response (DDR) target pipeline with the potential to transform cancer therapy visit website
Novel therapeutic modality to induce functional knockdown of a target protein visit website
Medical device company focused on spine products visit website
Bioabsorbable vessel closure devices to enable minimally invasive heart procedures visit website
Next generation immuno-modulators acting on adaptive and innate immunity visit website
Therapies for heart failure and related Cardiovascular Diseases visit website
Developing treatments for patients with hyperoxaluria visit website
Developing Protein Therapeutics for High Unmet Medical needs visit website
Next-generation neo-epitope vaccines and oncolytic viruses visit website
Reversed Merger 2019
Therapies for autoimmune and immunology related diseases
visit website
Development of drugs for orphan diseases visit website
IPO 2019
Treatment of improper fluid balances in the body
visit website
Reversed Merger 2017
Developing Therapeutics to treat genetic diseases
visit website
IPO 2017
Therapies for lysosomal storage - and protein misfolding diseases
visit website
Acquired by Codman Neuro 2017
Innovative devices for minimally invasive stroke therapy
Acquired by Smith & Nephew 2017
First treatment healing rotator cuff disease
visit website
User-friendly, appealing and highly accurate insulin patch pump therapy for diabetes patients. visit website
mRNA immunotherapies for oncology and infectious diseases visit website
ONWARD is creating technologies to improve the movement, independence, and health of people with spinal cord injury. visit website
Spontaneous growth of natural heart valves and vessels visit website
Ultra-rapid diagnosis of infections visit website
IPO 2017
Innovative immunology treatments to improve the lives of people suffering from severe autoimmune diseases and cancer.
Acquired by Bruker 2017
Light sheet microscopy
visit website
IPO 2016
Innovative full-length bispecific and trispecific antibody therapeutics for oncology.
visit website
IPO 2016
Ultra-rapid diagnosis of infections
IPO 2016
Orthobiological products for tissue and fracture repair
visit website
Minimally invasive treatment of bone fractures visit website
Minimally invasive reshaping of heart valve visit website
Prevention of drug misadministration at the bedside visit website
Treatment of severe hospitalized Influenza visit website
Next-generation glucose measuring devices visit website
Acquired by BioMarin 2015
Development of drugs for Duchenne Muscular Dystrophy
Acquired by Agilent Technologies 2015
Commercialization of medical instruments and laboratory products
visit website
Acquired by Intrexon (now Precigen) 2015
Oral delivery of complex biological medicines
visit website
IPO 2015
Novell cell therapies
visit website
Acquired by Medtronic 2014
Medical device for treatment of Parkinson's disease
Acquired by Vectura 2014
Novel medical solutions for lung disease
visit website
IPO 2014
Development of drugs for Alzheimer's disease
IPO 2014
Innovative treatments for heart disease
IPO 2014
Innovative cancer treatments
Acquired by Agenus 2014
Innovative cancer treatments
Acquired by GSK 2013
Breakthrough vaccines for infectious diseases
Acquired by Salix 2013
Novel treatments for specialist care
Acquired by Ipsen 2013
Novel treatment options for pain and inflammation
Acquired by Dr Reddy 2013
Preparation and development of injectable drugs
Acquired by Syngenta 2013
Next-generation crop protection
Acquired by Post foods 2013
Commercialization of probiotic foodbars
Acquired by LDC
Novel drugs for psychiatric disorders
visit website
Acquired by Syngenta 2012
Advanced crop protection technologies
Acquired by Tigenix 2011
Innovative treatments for bowel disorders and other diseases
Acquired by Edwards 2010
Commercialization of cardiovascular monitoring devices
Acquired by C.R. Bard 2010
State-of-the-art medical devices for heart disease
Acquired by Shire 2010
Innovative treatments for bowel disease
IPO 2010
Novel treatment options for diabetes and other diseases
visit website
IPO 2010
Development of drugs for rare and serious diseases
Acquired by Cosmo 2009
Novel drugs for bladder disorders and inflammatory diseases
Acquired by Daiichi Sankyo 2008
Innovative cancer treatments
IPO 2007
Advanced platform technologies to enable the development of drugs
visit website
Acquired by Shire 2006
Development of drug for rare and fatal disease
Acquired by Pharming 2006
Products for medical problems associated with aging
Acquired by Astra Zeneca 2006
Innovative cancer treatments
IPO 2000
Development of vaccines
IPO 1999
Commercialization of vaccines for infectious disease
IPO 2000
Precise identification of diseases and disorders in humans
IPO 1996
Diagnostics and laboratory testing equipment
Acquired by Leica
Labeling and detection of biological molecules
visit website
Merged with U-Bisys into Crucell
Development of vaccines
Acquired by Bioness
Innovative rehabilitation products
IPO
Drug formulation
Acquired by Straumann
Commercialization of products used by dentists and oral surgeons
Merged with Introgene into Crucell
Innovative drug development platform